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About this product
Product Identifiers
PublisherSpringer Berlin / Heidelberg
ISBN-103662102110
ISBN-139783662102114
eBay Product ID (ePID)203322171
Product Key Features
Number of PagesXx, 279 Pages
Publication NameTacrolimus Ointment : a Topical Immunomodulator for Atopic Dermatitis
LanguageEnglish
Publication Year2014
SubjectDermatology
TypeTextbook
Subject AreaMedical
AuthorS. Reitamo
FormatTrade Paperback
Dimensions
Item Weight23.1 Oz
Item Length10 in
Item Width8 in
Additional Product Features
Intended AudienceScholarly & Professional
Number of Volumes1 vol.
IllustratedYes
Table Of ContentAtopic Dermatitis I.- 1 Epidemiology of Atopic Dermatitis.- 2 The Pathogenesis of the Atopic Eczema/Dermatitis Syndrome.- 3 Detecting, Diagnosing and Grading Atopic Dermatitis.- 4 Current Treatment of Atopic Dermatitis.- Development of Tacrolimus Ointment II.- 5 Development of Tacrolimus Ointment.- 6 Pharmacokinetics of Tacrolimus Ointment: Clinical Relevance.- 7 Tacrolimus as an Immunomodulator.- III Clinical Experience with Tacrolimus Ointment in Atopic Dermatitis.- 8 Clinical Experience in Adults.- 9 Clinical Experience in Children.- 10 The Role of Tacrolimus Ointment in Atopic Dermatitis.- 11 Other Potential Dermatological Indications for Tacrolimus.- IV Social Impact of Atopic Dermatitis.- 12 Quality of Life Measurements in Atopic Dermatitis.- 13 Pharmacoeconomics in Atopic Dermatitis.- Appendix V.
SynopsisTherapeutic breakthroughs in medicine are usually accompanied by a wealth of data. Often they result in a change of disease treatment paradigms. Tacrolimus ointment is the first in the new class of steroid-free Topical Immunomodulators (TIMs), and as such represents the first true breakthrough since the introduction of topical steroids more than 50 years ago for the treatment of T-cell mediated inflammatory skin diseases such as atopic dermatitis. This book gives an easy-to-read overview of the discovery and the development of Tacrolimus ointment for the treatment of atopic dermatitis. Summarising the largest clinical trial program ever conducted in dermatology for a new treatment with more than 13000 patients, it offers a detailed insight into the efficacy and safety profile of Tacrolimus ointment. Based on this large body of data and extensive personal experience, the authors offer practical and hands-on guidance for the physician as to when and how to use Tacrolimus ointment in daily practice.